2025

Intracellular protein-lipid interactions drive presynaptic assembly prior to neurexin recruitment.

Frankel EB, Tiroumalechetty A, Su Z, Henry PS, Mueller BD, Jorgensen EM, Wu Y, Kurshan PT.

Neuron 2025 Mar 5;113, 1–17. doi: 10.1016/j.neuron.2024.12.017.

2024

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly.

Schaan Profes M, Tiroumalechetty A, Patel N, Lauar SS, Sidoli S, Kurshan PT.

PLoS Biol. 2024 January 22;22(1): e3002466. doi: 10.1371/journal.pbio.3002466. 

Editorial: The role of trafficking in synaptic development, maintenance, and plasticity.

Hoerndli FJ, Kurshan PT, Anggono V.

Front Cell Neurosci. 2024 Jan 10;18:1362676. doi: 10.3389/fncel.2024.1362676.

2023

C. elegans Clarinet/CLA-1 recruits RIMB-1/RIM-binding protein and UNC-13 to orchestrate presynaptic neurotransmitter release.

Krout M, Oh KH, Xiong A, Frankel EB, Kurshan PT, Kim H, Richmond JE.

Proc Natl Acad Sci U S A 2023 May 23;120(21)::e2220856120. doi: 10.1073/pnas.2220856120.

2020

All Talk, No Assembly: Voltage-Gated Calcium Channels Do Not Mediate Active Zone Formation.

Frankel EB, Kurshan PT.

Neuron 2020 Aug 19;107(4):593-594. doi: 10.1016/j.neuron.2020.07.028.

2019

Synaptogenic pathways.

Kurshan PT, Shen K.

Curr Opin Neurobiol. 2019 Apr 12;57:156-162. doi: 10.1016/j.conb.2019.03.005. Review.

2018

γ-Neurexin and Frizzled Mediate Parallel Synapse Assembly Pathways Antagonized by Receptor Endocytosis.

Kurshan PT, Merrill SA, Dong Y, Ding C, Hammarlund M, Bai J, Jorgensen EM, Shen K.

Neuron. 2018 Oct 10;100(1):150-166.e4. doi: 10.1016/j.neuron.2018.09.007.

2017

Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release.

Xuan Z, Manning L, Nelson J, Richmond JE, Colón-Ramos DA, Shen K, Kurshan PT.

Elife. 2017 Nov 21;6. pii: e29276. doi: 10.7554/eLife.29276. Free PMC Article

For a full list of publications see PubMed profile